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Mometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, MORFEX 5/100 MCG INHALASYON IÇIN ÖLÇÜLÜ DOZLU AEROSOL ,120 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer.
Synonyms: (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (+)-(S)-p-isobutylhydratropic acidMixtures: TAFLAX® GRIP, TAFLAX®FORTE TABLETAS RECUBIERTASFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnFlupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. … Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid.
Mixtures: DORMIR TABLET, 20 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingSapropterin
go.drugbank.com/drugs/DB00360ApprovedInvestigationalSapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. … It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingSynonyms: (6R)-L-erythro-tetrahydrobiopterin, 6R-L-5,6,7,8-tetrahydrobiopterinMethylergometrine
go.drugbank.com/drugs/DB00353ApprovedInvestigationalA homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide, D-lysergic acid 1-butanolamidePapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalIt is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. … An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions.
Categories: Heterocyclic Compounds, 2-RingProducts: PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 100 ADET, PAPAVERIN HIDROKLORUR 0.06 G/2 ML BIOSEL AMPUL, 100 ADETSoybean oil
go.drugbank.com/drugs/DB09422ApprovedInvestigationalIt is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. … Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids.
Mixtures: SMOFlipid 200 mg/ml Emulsion zur Infusion, LIPOFUNDIN MCT/LCT %20 VIT E INFUZYON ICIN YAG EMULSUYONU, 100 MLProducts: INTRALIPID %20 100 ML YAG EMULSIYONU, CELEPID® 10%Rivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsProducts: RIVAROX® 20 MG, Rivaroxaban 1A Pharma 20 mg - FilmtablettenCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
Synonyms: Platinum, diammine [1,1-cyclobutane-dicarboxylato(2-)-0,0']-,(SP-4-2)International brands: Paraplatin AQ, Paraplatin-AQGliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationalGliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%). … a sulfonamide group able to release a proton and the presence of one aromatic group.
Mixtures: DUODİA 80 MG/500 MG TABLET, 30 ADET, DUODIA 80/500 MG TABLET, 60 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates