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Ocrelizumab
go.drugbank.com/drugs/DB11988ApprovedInvestigationalIt was later approved by Health Canada in August 2017, making the drug the first available treatment for PPMS in both the US and Canada. … Primary progressive multiple sclerosis (PPMS) accounts for 10-15% of the overall population of patients with MS, and leads to the gradual worsening of neurologic disability from symptom onset, often without
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: OCREVUS 300mg/10mL Concentrate for Solution for Infusion, OCREVUS® CONCENTRADO PARA SOLUCION PARA INFUSION 300MG/10MLAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigational[A232960] On August 6, 2021, avalglucosidase alfa-ngpt was approved by the FDA under the market name Nexviazyme to treat patients one year of age and older with late-onset Pompe disease. … Pompe disease is characterized by progressive muscle weakness and loss of motor function, including respiratory muscle weakness, which leads to premature death and debilitating effects on people’s lives
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: NEXVIAZYME 100mg Powder for Concentrate for Solution for InfusionCytisus scoparius flowering top
go.drugbank.com/drugs/DB11007ApprovedCytisus scoparius flowering top allergenic extract is used in allergenic testing.
Products: Pollens - Weeds and Garden Plants, Scotch Broom Cytisus scopariusSalmon, unspecified
go.drugbank.com/drugs/DB11014ApprovedSalmon, unspecified allergenic extract is used in allergenic testing.
Products: Food - Fish and Shellfish, Salmon Salmo salarMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Products: MIANSERIN 10MG HOLSTEN, MIANSERIN-REMEDICA 10mg Film-Coated TabletsCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigational[A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998. … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon.
Categories: tramadol and celecoxib, amlodipine and celecoxibProducts: CELEBREX 100MG, CELECOX 100MGPhoma exigua var. exigua
go.drugbank.com/drugs/DB10440ApprovedPhoma exigua var. exigua is a fungus which can provoke allergic reactions. Phoma exigua var. exigua extract is used in allergenic testing.
Products: Molds, Rusts and Smuts, Phoma herbarumAcarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigational[L31633,A37868] By inhibiting the activity of these enzymes, acarbose limits the absorption of dietary carbohydrates and the subsequent postprandial increase in blood glucose and insulin levels. … starches and oligo-, tri-, and disaccharides into absorbable simple sugars.
Categories: metformin and acarbose, Alimentary Tract and MetabolismProducts: GLUCOBAY TABLET 100MG, Gacose Tablet 100mgAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalIt stimulates synthesis and release of surfactant by type II pneumocytes. … Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.
Mixtures: MUCOSOLVAN®COMPOSITUM GOTAS 15MG/0.01MG/2MLCategories: Cough and Cold Preparations, clenbuterol and ambroxolPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigational(From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: LOKARIL % 5 KREM ,10G, ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit)Products: TAKIPRIL SOLUTION FOR INJECTION 20MG/ML, Takipril 20mg/ml Solution for Injection