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Hyperforin
go.drugbank.com/drugs/DB01892InvestigationalNutraceuticalOne of the most important members of this family, due to its medical properties, is _Hypericum perforatum_, also known as St John's wort.
Isradipine
go.drugbank.com/drugs/DB00270ApprovedIsradipine may be used to treat mild to moderate essential hypertension. … Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs.
Telotristat ethyl
go.drugbank.com/drugs/DB12095Approved[L43367] Overexposure to serotonin can cause severe diarrhea, one of the main clinical symptoms of carcinoid syndrome. … [L43342] Neuroendocrine cells are cells that secrete regulatory peptides and biogenic amines in response to chemical, neural, or other types of stimuli.
Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
go.drugbank.com/drugs/DB16757Approved[A245824] In addition, VLPs contain no viral material and are therefore inherently non-infectious, making them potentially safer alternatives to traditional vaccines.[A245824] … [A245819] Plant-based VLPs offer a number of advantages as compared to other vaccine platforms, including speed and ease of manufacturing and increased immunogenicity.
Oxymetholone
go.drugbank.com/drugs/DB06412ApprovedIllicitThe uncontrolled misuse of oxymetholone can lead to a large variety of detrimental effects, the most often reported of which are cardiovascular events. … In 2009, no producers of oxymetholone were identified worldwide (SRI 2009), but it was available from 14 suppliers, including 8 U.S. suppliers (ChemSources 2009).
Albuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedThis lead to the development of levalbuterol, the single R-isomer of salbutamol. … However, the high cost of levalbuterol compared to salbutamol has deterred wide-spread use of this enantiomerically pure version of the drug.
Categories: Agents to Treat Airway DiseaseProducts: VENTOLIN RESPIRATOR SOLUTION 0.5% w/v, PHARMANIAGA SALBUTAMOL RESPIRATOR SOLUTION 0.5% W/VTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalIt is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension.
Products: TRAVO EYE DROPS 0.004% W/V, TRAVOPROST DOC GENERICIAzilsartan medoxomil
go.drugbank.com/drugs/DB08822ApprovedInvestigational[L32918] Azilsartan medoxomil is thus speculated to lower mortality rates and the onset of cardiovascular disease. … Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class.
Vasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigational[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. … Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation
Mirdametinib
go.drugbank.com/drugs/DB07101ApprovedInvestigational[L52485] NF1 is an autosomal-dominant genetic condition caused by loss-of-function variants in the _NF1_ tumour suppressor gene,[A265065,A265070] leading to neurofibromin dysfunction and aberrant activation