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Displaying results 1061 - 1070 of 10000 in total
  1. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Synonyms: Antithrombin III (human) concentrate IV, AT-IIIProducts: KYBERNIN P 500 IU IV ENJEKSİYONLUK İNFÜZYONLUK LİYOFİLİZE TOZ VE ÇÖZÜCÜ, AT III KEDRION
  2. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

    International brands: Slow-K, Micro-KMixtures: Plasma-Lyte A, Plasma-Lyte A
  3. Target

    Streptogramin A acetyltransferase

    go.drugbank.com/bio_entities/BE0001238
    TargetEnterococcus faecium

    Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.

    Polypeptides: Streptogramin A acetyltransferase
  4. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001365
    TargetProsthecochloris aestuarii

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  5. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001804
    TargetPaenibacillus polymyxa

    BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.

    Polypeptides: Beta-glucosidase A
  6. Target

    GABA(A) Receptor

    go.drugbank.com/bio_entities/BE0004797
    TargetHumans

    Extrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … Plays an important role in somatosensation and in the production of antinociception (By similarity)

    Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activity
  7. Target

    Apolipoprotein A-IV

    go.drugbank.com/bio_entities/BE0009049
    TargetHumans

    May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. … Apoa-IV is a major component of HDL and chylomicrons

    Polypeptides: Apolipoprotein A-IV
  8. Target

    HSP40, subfamily A

    go.drugbank.com/bio_entities/BE0009270
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: HSP40, subfamily ASynonyms: HSP40, subfamily A, putative
  9. Drug

    Carboplatin

    go.drugbank.com/drugs/DB00958
    ApprovedInvestigational

    Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]

    Synonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)International brands: Paraplatin AQ, Paraplatin-AQ
  10. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index