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Displaying results 1061 - 1070 of 10000 in total
  1. Drug

    Peppermint oil

    go.drugbank.com/drugs/DB11198
    ApprovedInvestigational

    , thereby facilitating its effect in the lower GI tract without effects in the upper tract [A33055]. … Due to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized

    Synonyms: Oil of peppermint, Mentha X piperita oilMixtures: Cellzyme ON-TOX, Cellzyme ON-TOX
  2. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380] … [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.

    Mixtures: DORZOLAMIDE E TIMOLOLO MYLAN GENERICS, DORZOLAMIDE E TIMOLOLO MYLAN GENERICSCategories: combinations of sulfonamides, Cytochrome P-450 Substrates
  3. Drug

    Sodium ferric gluconate complex

    go.drugbank.com/drugs/DB09517
    Approved

    It is used in adult and in pediatric patients over the age of 6 years with chronic kidney disease (CKD) receiving hemodialysis and receiving supplemental epoetin therapy. … It is composed of iron (III) oxide hydrate directly bonded to sucrose with a chelating gluconate function in a molar ratio of two iron molecules to one gluconate.

    Products: Sodium Ferric Gluconate Complex in Sucrose
  4. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    the public in 1998 [A175732], continues to see millions of prescriptions written for it internationally. … The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth muscle relaxation and vasodilation that subsequently facilitates relief in pulmonary arterial hypertension

    Synonyms: 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazineMixtures: DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLET
  5. Drug

    Albumin human

    go.drugbank.com/drugs/DB00062
    ApprovedInvestigational

    Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III). … Also known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229].

    Products: HI-BUMIN, Rhophylac 300 Mikrogramm / 2 ml Injektionslösung in einer Fertigspritze
  6. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. … Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated.

    Synonyms: thiamine(1+) ion, Vitamin B 1International brands: Betalin S
  7. Drug

    Cocoa butter

    go.drugbank.com/drugs/DB11086
    Approved

    Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products. … While cocoa butter has skin moisturizing properties, it was not shown to reduce the likelihood of developing of striae gravidarum, or stretch marks, in a double-blind, randomized clinical trial of women

    Mixtures: Calmol 4, Preparation HProducts: Coconut Cosmetics 3-in-1 Serum, Dermatitica Synergy for treatment of Dermatitis
  8. Drug

    Alfacalcidol

    go.drugbank.com/drugs/DB01436
    ApprovedInvestigationalNutraceutical

    Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback mechanism regulates the final activation step of vitamin D in the kidneys.

    Synonyms: 1-hydroxycholecalciferol, 1α-hydroxyvitamin D3Categories: Vitamin D and Analogues, Drugs for Treatment of Bone Diseases
  9. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … It is metabolized to its biologically active diacid form, trandolaprilat, in the liver.

    Mixtures: TARKA® SR240/4 TABLETAS., TARKA® SR TABLETASCategories: Agents Acting on the Renin-Angiotensin System, Heterocyclic Compounds, 2-Ring
  10. Drug

    Conivaptan

    go.drugbank.com/drugs/DB00872
    Approved

    It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin).

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide