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Bendazac
go.drugbank.com/drugs/DB13501ApprovedWithdrawnBendazac is an oxyacetic acid [A39863, A39869]. … the denaturation of proteins - an effect that has primarily proven useful in managing and delaying the progression of ocular cataracts [A39863.
Categories: Non COX-2 selective NSAIDS, Analgesics, Non-NarcoticDupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt is currently used to treat atopic dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and eosinophilic esophagitis. … [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017.
Categories: Interleukin-4 Receptor alpha Antagonist, Interleukin 4 Receptor alpha AntagonistsProducts: DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml, DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14mlRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigationalelevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. … [A181523] This last point results in less risk of drug-drug interactions compared to [atorvastatin], [lovastatin], and [simvastatin], which are all extensively metabolized by Cytochrome P450 (CYP) 3A4,
Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Categories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesNialamide
go.drugbank.com/drugs/DB04820ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Categories: Heterocyclic Compounds, 1-Ring, Monoamine Oxidase Inhibitors, Non-SelectiveSynonyms: N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine, N-(2-(Benzylcarbamyl)ethylamino)isonicotinamideNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
go.drugbank.com/bio_entities/BE0000295TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B15NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
go.drugbank.com/bio_entities/BE0000338TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-MNLLTGF-beta receptor type-1
go.drugbank.com/bio_entities/BE0003782TargetHumansTransmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signa...
Synonyms: TbetaR-I, TGF-beta receptor type IEthylhexyl methoxycrylene
go.drugbank.com/drugs/DB11226ApprovedEthylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states [F104]. … It returns UV filters to their ground states without absorbing sunlight [F104].
Bunamiodyl
go.drugbank.com/drugs/DB04814ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to nephropathy.
Synonyms: 2-(3-Butyramido-3,4,6-triiodophenylmethylene)butyric acidOxeladin
go.drugbank.com/drugs/DB04822ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity.
Synonyms: 2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate