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Technetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160ApprovedThe radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. … [A31592] Technetium Tc-99m tetrofosmin was developed by GE Healthcare and FDA approved on February 9, 1996.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsIron Dextran
go.drugbank.com/drugs/DB00893ApprovedInvestigationalVet approvedIron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. … Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Mixtures: PureFe OB Plus, Prefera OB plus DHACategories: Compounds used in a research, industrial, or household settingTrovafloxacin
go.drugbank.com/drugs/DB00685ApprovedWithdrawnDue to its hepatotoxic potential, trovafloxacin was withdrawn from the market. … Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer.
Gallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation … Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67.
Tegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalensuring high concentrations of 5-FU at a lower dose of tegafur [L933]. … Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers.
Mixtures: TS-ONE OD Tablet 20, TS-ONE OD Tablet 25Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexSodium phosphate, monobasic
go.drugbank.com/drugs/DB09449ApprovedInvestigationalSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Mixtures: Urin D/S, Uretron D/SCategories: Drugs for Treatment of HypercalcemiaNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawn[L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. … Nalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist.
Categories: Heterocyclic Compounds with 4 or More RingsNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigational[A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.
Categories: Sex Hormones and Modulators of the Genital SystemSynonyms: 17-α-ethynyl-4-estren-17-ol-3-one, 17α-ethynyl-4-estren-17-ol-3-oneSulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalSulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. … This may be due to the sulfide metabolite undergoing enterohepatic circulation thus maintaining constant blood levels of the compound without inducing gastrointestinal effects, where the drug is excreted
Products: Nu-sulindac Tab 150mg, Nu-sulindac Tab 200mgTazemetostat
go.drugbank.com/drugs/DB12887ApprovedInvestigationalTazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. … [L11476] Tazemetostat was first named in literature as EPZ-6438.[A190363] Tazemetaostat was granted FDA approval on 23 January 2020.[L11476]