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Grape seed oil
go.drugbank.com/drugs/DB14323InvestigationalGrape seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Grape Seed OilNuclear factor NF-kappa-B complex
go.drugbank.com/bio_entities/BE0009554TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Thiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalIt is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663] … Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_.
Products: KENFIX 4 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 6 AMPUL, KEYRELAKS 4 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 6 AMPULHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Products: Atarax Im Sol 50mg/ml, AA PHARMA HYDROXYZINE CAPSULE 10 mgClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedThis drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].
Mixtures: SAEROGENTA-A CREAM, Creobic DA (Double Action) CreamProducts: CLOTRIMAZOLO IG FARMACEUTICI, Terrasil Tinea Treatment MAXCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigationalCarbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. … therapy developed by Mayne Pharma in 1992.
Synonyms: L-α-methyldopahydrazine, L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acidMixtures: LEVO/CA/EN 100/25/200 STD, LEVO/CA/EN 150/37.5/200STDPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
go.drugbank.com/bio_entities/BE0005530TargetHumansInvolved in the regulation of synaptic function in excitatory hippocampal synapses. … May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
Synonyms: Mutated in multiple advanced cancers 1tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
go.drugbank.com/bio_entities/BE0020091EnzymeHumansSpecifically modifies U20 in cytoplasmic tRNAs (PubMed:38680565). Activity depends on the presence of guanosine at position 19 in the tRNA substrate (PubMed:38680565). … Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565).
Synonyms: Up-regulated in lung cancer protein 8Glucosamine
go.drugbank.com/drugs/DB01296Approved[A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter. … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.
Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Procosa II Tablet, Nn Bio-Glucosamine 500 Tablet