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Cefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigationalCefepime is a fourth-generation cephalosporin antibiotic developed in 1994. … [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical
Synonyms: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateProducts: Maxipime for Injection -pws IV Im 1g, UNİSEF 1 G IM/IV ENJEKTABL TOZ İÇEREN FLAKONCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigationaldone directly in bacterial hosts such as _E. coli_. … [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated for a new indication on March 28, 2019.[L5819]
Products: CIMZIA 200 MG ILO IN FER, CIMZIA 200MG ILO IN FERGadodiamide
go.drugbank.com/drugs/DB00225ApprovedInvestigationalGadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels. … [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used.
Categories: Compounds used in a research, industrial, or household settingProducts: Omniscan Liq IV 287mg/ml, SCANIX 287 MG/ML IV ENJEKSİYONİÇİN ÇÖZELTİ İÇEREN FLAKON, 10 MLHuman immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. … IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population.
Mixtures: Iveegam Immuno 5000mg (iv)Products: IG VENA5 G / 100 ML, IG VENA 1 G / 20 MLDobutamine
go.drugbank.com/drugs/DB00841ApprovedInvestigationalIt is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Mixtures: Dobutamine Hydrochloride in Dextrose, DOCARIP® 1 MG/MLCategories: Compounds used in a research, industrial, or household settingEsmolol
go.drugbank.com/drugs/DB00187ApprovedInvestigationalWithdrawnIt works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate of heart contractions. … Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker.
Products: Brevibloc Liq IV 10mg/ml, Brevibloc Liq IV 250mg/mlHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigational[F4645] It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic. … [A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s.[A180610]
Products: -im 50mg/ml, -im 100mg/mlPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.
Products: INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml, INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 mlTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigational[L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. … Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions.
Products: ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET, ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADETUstekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigationalUstekinumab is a fully human immunoglobulin G1 kappa monoclonal antibody that binds the shared p40 subunit of interleukin (IL)-12 and IL-23. … [L64773] The FDA approved it for adults with moderately to severely active ulcerative colitis in October 2019.
Products: STELARA IV, Steqeyma IV