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Displaying results 101 - 110 of 158651 in total
  1. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

    Mixtures: Medi-10, S-pan-M TabCategories: Heterocyclic Compounds, 1-Ring, Vitamin B Complex
  2. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998].

    Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 5'-Noranhydrovinblastine
  3. Drug

    3-carboxamido-1,3,5(10)-estratrien-17(R)-spiro-2'(5',5'-dimethyl-6'oxo)tetrahydropyran

    go.drugbank.com/drugs/DB07700
    Experimental

  4. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … failure, bladder cancer) and the availability of safer and more effective alternatives for patients with type 2 diabetes mellitus.

    Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and Metabolism
  5. Drug

    Sulfisoxazole

    go.drugbank.com/drugs/DB00263
    ApprovedVet approved

    A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

    Categories: Sulfonamides and trimethoprim, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamide
  6. Drug

    Butalbital

    go.drugbank.com/drugs/DB00241
    ApprovedIllicit

    Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index.

    Mixtures: Butalbital and Acetaminophen 50 mg/325 mg, Fiorinal-C 1/4Categories: Heterocyclic Compounds, 1-Ring, Hypnotics and Sedatives
  7. Drug

    Floxuridine

    go.drugbank.com/drugs/DB00322
    ApprovedInvestigational

    Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. … It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

    Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsSynonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil
  8. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Synonyms: (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester, O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamateInternational brands: Ben-A
  9. Drug

    Dacarbazine

    go.drugbank.com/drugs/DB00851
    ApprovedInvestigational

    An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.

    Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsSynonyms: 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide
  10. Drug

    Thiamylal

    go.drugbank.com/drugs/DB01154
    ApprovedVet approved

    A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state.

    Categories: Heterocyclic Compounds, 1-Ring, Hypnotics and SedativesSynonyms: 5-allyl-5-(1-methylbutyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione, 5-allyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione