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Adenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 5'-AMP, Adenosine-5'PPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence … [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis.
Mixtures: DROPIA-MET 15/850 MG FILM TABLET, 180 ADET, PIO-MET 15/500 MG FILM TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester, O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamateInternational brands: Ben-A9-(2-carboxyethyl)-10-methylanthracene endoperoxide
go.drugbank.com/drugs/DB08332ExperimentalSynonyms: 9-(2-carboxyethyl)-10-methylanthracene endoperoxide, [2'-CARBOXYLETHYL]-10-METHYL-ANTHRACENE ENDOPEROXIDEVinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].
Synonyms: 5'-NoranhydrovinblastineCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates(10R)-10-formyl-5,8,10-trideazafolic acid
go.drugbank.com/drugs/DB04264ExperimentalSynonyms: (10R)-10-formyl-5,8,10-trideazafolic acidSulfisoxazole
go.drugbank.com/drugs/DB00263ApprovedVet approvedA short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.
Synonyms: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulphonamideCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsButalbital
go.drugbank.com/drugs/DB00241ApprovedIllicitButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from mild sedation
Synonyms: 5-allyl-5-isobutyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(2-methylpropyl)barbituric acidMixtures: Butalbital and Acetaminophen 50 mg/325 mg, Fiorinal-C 1/4Floxuridine
go.drugbank.com/drugs/DB00322ApprovedInvestigationalFloxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. … When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil3-carboxamido-1,3,5(10)-estratrien-17(R)-spiro-2'(5',5'-dimethyl-6'oxo)tetrahydropyran
go.drugbank.com/drugs/DB07700Experimental