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Displaying results 1091 - 1100 of 10000 in total
  1. Drug

    Brivudine monophosphate

    go.drugbank.com/drugs/DB04438
    Experimental

    Synonyms: Bvdu 5'-monophosphate, BVDU-MP
  2. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate, 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester
  3. Drug

    D-Glutamine

    go.drugbank.com/drugs/DB02174
    Experimental

    A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. … It is the principal carrier of nitrogen in the body and is an important energy source for many cells.

    Synonyms: D-Glutaminsäure-5-amid, (R)-2,5-diamino-5-oxopentanoic acid
  4. Drug

    Robalzotan

    go.drugbank.com/drugs/DB06538
    Experimental

    Synonyms: (R)-3-(Dicyclobutylamino)-8-fluoro-5-chromancarboxamideCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor Antagonists
  5. Drug

    Oxfendazole

    go.drugbank.com/drugs/DB11446
    InvestigationalVet approved

    Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole, 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester
  6. Drug

    Bazlitoran

    go.drugbank.com/drugs/DB14990
    Investigational

    Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).

    Synonyms: ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL, -(3'->5')-2'-O-METHYL-P-THIOURIDYLYL-(
  7. Drug

    DSP-5336

    go.drugbank.com/drugs/DB18514
    Investigational

    DSP-5336 is a menin inhibitor.

    Synonyms: BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO(3.5)NON-2-YL)-5-PYRIMIDINYL)OXY)-N,N-BIS(1-METHYLETHYL)-
  8. Drug

    (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone

    go.drugbank.com/drugs/DB04135
    Experimental

    Synonyms: (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone, (4S)-5-Fluoro-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one
  9. Drug

    D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide

    go.drugbank.com/drugs/DB02038
    Experimental

    Synonyms: D-pyridoxyl-N,O-cycloserylamide-5-monophosphate, D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide
  10. Drug

    Sevasemten

    go.drugbank.com/drugs/DB18983
    Investigational

    Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one