Search

Displaying results 1091 - 1100 of 10000 in total
  1. Pathway

    Gs Histaminic Smooth Muscle Relaxation

    smpdb.ca/view/SMP0126967
    Physiological

    The Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα is the foundin...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  2. Target

    Leukocyte surface antigen CD47

    go.drugbank.com/bio_entities/BE0010649
    TargetHumans

    Adhesive protein that mediates cell-to-cell interactions (PubMed:11509594, PubMed:15383453). Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins (PubMed:1...

    Synonyms: MER6, Protein MER6
  3. Pathway

    Celiprolol B2-Adrenergic Vasodilation Action Pathway

    smpdb.ca/view/SMP0126095
    Drug action

    Celiprolol is a selective beta-1 adrenergic receptor antagonist and a beta-2 adrenergic receptor partial agonist that is used for the management of hypertension and angina pectoris. The beta-2 adrenergic receptor agonist activity is attr...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Celiprolol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  4. Pathway

    Fenoterol Action Pathway

    smpdb.ca/view/SMP0126100
    Drug action

    Fenoterol is a short acting beta-2 adrenergic receptor agonist that is used as a bronchodilator. This drug causes the relaxation of bronchial smooth muscle allowing for its use for the treatment of asthma. The result of taking this drug ...

    Drugs: ATP · Fenoterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  5. Pathway

    Pirbuterol Action Pathway

    smpdb.ca/view/SMP0126102
    Drug action

    Pirbuterol is a beta-2 adrenergic agonist that has a preferential effect. It is a short acting, inhaled drug that causes bronchial smooth muscle relaxation through stimulation of adenylyl cyclase. It is used as a bronchodilator for the t...

    Drugs: ATP · Pirbuterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  6. Pathway

    Racepinephrine B2-Adrenergic Bronchodilation Action Pathway

    smpdb.ca/view/SMP0126107
    Drug action

    Racepinephrine is a bronchodilator used to treat asthma. It can be found under the brand name Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a rapid onset and short duration and acts ...

    Drugs: ATP · Epinephrine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  7. Pathway

    Etafedrine Action Pathway

    smpdb.ca/view/SMP0126114
    Drug action

    Etafedrine is a beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa. It can be found under the brand name Dalmacol and is a long acting bronchodilator that relaxes the smooth muscle of the lungs. It can be u...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  8. Drug

    ISTH0036

    go.drugbank.com/drugs/DB18606
    Investigational

    ISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA

  9. Pathway

    Orciprenaline Action Pathway

    smpdb.ca/view/SMP0126083
    Drug action

    Orciprenaline is a beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. This drug is used exclusively as a bronchodilator. When taken, it acts on the smooth muscles in the bronchi causing a muscle relaxation or broncho...

    Drugs: ATP · Orciprenaline · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  10. Pathway

    Salmeterol Action Pathway

    smpdb.ca/view/SMP0126085
    Drug action

    Salmeterol is a long acting beta-2 adrenergic receptor agonists used to treat asthma and COPD. Beta-2 agonists are G protein linked second messengers. It can be found under the brand names Advair, Airduo, Serevent, and Wixela. This drug ...

    Drugs: ATP · Salmeterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12