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Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Mixtures: Combipres 0.1/15 TabCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistMethapyrilene
go.drugbank.com/drugs/DB04819ApprovedWithdrawnMethapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine, N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamineOxfendazole
go.drugbank.com/drugs/DB11446InvestigationalVet approvedOxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole, 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl esterAdenosine 3',5'-diphosphate
go.drugbank.com/drugs/DB01812ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-ADP, 3'-Phosphoadenosine 5'-phosphateCysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigationalCystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. … [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis.
Synonyms: 2-amino-1-ethanethiol, 2-aminoethanethiolProducts: CYSTAGON ® 50 MG CAPSULAS, CYSTAGON ® 150 MG3-amino-5-phenylpentane
go.drugbank.com/drugs/DB02869Experimentaland cathepsin L2. … 3-amino-5-phenylpentane is a solid. This compound belongs to the phenylpropylamines.
Synonyms: 3-amino-5-phenylpentaneBufotenine
go.drugbank.com/drugs/DB01445ExperimentalIllicitBufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor AntagonistsSynonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-ol5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione
go.drugbank.com/drugs/DB03368ExperimentalSynonyms: 5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-TrioneHUB-101
go.drugbank.com/drugs/DB18656ExperimentalSynonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide
go.drugbank.com/drugs/DB04278ExperimentalSynonyms: N-{(2R)-2-Cyclohexyl-2-[(diaminomethylene)amino]acetyl}glycyl-N-(3-sulfanylpropyl)-L-alaninamide, 2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide