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Mycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigationalMycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. … Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.
Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acidZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesSynonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateSodium fluoride
go.drugbank.com/drugs/DB09325ApprovedInvestigationalSodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care.
Mixtures: O-Cal FA multivitamin, O-Cal FA multivitaminCategories: Compounds used in a research, industrial, or household settingBendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalBendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). … Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, BEASTIN 25 MG I.V. INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADETRecurrent Miscarriages
go.drugbank.com/conditions/DBCOND0032265Drugs: DydrogesteroneSynonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy lossAmino acids
go.drugbank.com/drugs/DB09393InvestigationalMixture of amino acids ; used for parenteral nutrition in infants.
Mixtures: Clinimix 3 % G-E - Infusionsbeutel, Clinimix 5 % G-E - InfusionsbeutelProducts: AMINOACIDI A CATENA RAMIFICATA, AMINOACIDI A CATENA RAMIFICATA MONICODocusate
go.drugbank.com/drugs/DB11089ApprovedDocusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201]. … Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative.
Mixtures: FeRiva FA, Senna-SProducts: Lax-A Soft, Nra-docusate SodiumTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedAs with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.
Categories: Non COX-2 selective NSAIDSProducts: Antiphlogistine Rub A-535 No Odour Fmla Ont, Arthritis Relief Well At WalgreensLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing downstream modulation of both gonadotropin hormone and sex steroid levels. … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH).
Categories: Gonadotropin Releasing Hormone Receptor Agonist, Gonadotropin Releasing Hormone Receptor AgonistsInternational brands: Prostap 3Propafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Categories: Antiarrhythmics, Class I, P-glycoprotein inhibitorsSynonyms: 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone, 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone