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Ritonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalRitonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. … The inclusion of ritonavir can select for HIV-1 protease inhibitor resistance-associated substitutions.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalis indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE … In addition to once daily dosing, the benefits over warfarin also include significant reductions in hemorrhagic stroke and GI bleeding, and improved compliance, which is beneficial as many patients will
Categories: P-glycoprotein substratesProducts: Ag-edoxabanOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. … [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning.
Products: Oxyla 10 IU/mL Injection, SYNTOCINON INJECTION 10 iu/mlAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesEnfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigationalEnfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTrolamine polypeptide oleate condensate
go.drugbank.com/drugs/DB09373ApprovedVet approvedVarious ear diseases and infections are treated with eardrops containing triethanolamine polypeptide oleate-condensate, such as Cerumenex in the United States and Canada.
Bromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.
Mixtures: BODREX FLU & BATUK BERDAHAK PE, TUSSIONEX DUO JARABEProducts: HUSTAB PEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedEpinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. … It can be used in severe cases of croup [L4824].
Mixtures: D-Care 100X, Ultracaine DS InjCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigationalEnoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection an...
Products: CLEXANE ® 300 MG/ 3 ML VIAL, CLEXANE INJECTION 2000 IU (20mg)/0.2 mlCY 1899
go.drugbank.com/drugs/DB17797ExperimentalSynonyms: IMMUNOTHERAPEUTIC VACCINE CONSISTING OF (PAM)2-LYS-SER-SER-GLN-TYR-ILE-LYS-ALA-ASN-SER-LYS-PHE-ILE-GLY-ILE-THR-GLU-ALA-ALA-ALA-PHE-LEU-PRO-SER-ASP-PHE-PHE-PRO-SER-VAL