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Endoscopic Diagnosis in Esophagus
go.drugbank.com/conditions/DBCOND0084643Drugs: RanitidineSynonyms: Endoscopic Diagnosis in EsophagusBleeding in invasive procedures
go.drugbank.com/conditions/DBCOND0106041Drugs: LusutrombopagSynonyms: Bleeding in invasive proceduresMutation in SMN1 gene
go.drugbank.com/conditions/DBCOND0173803Drugs: Onasemnogene abeparvovecSynonyms: Mutation in SMN1 geneLipegfilgrastim
go.drugbank.com/drugs/DB13200ApprovedLipegfilgrastim is a covalent conjugate of [DB00099] with a single methoxy polyethylene glycol (PEG) molecule via a carbohydrate linker consisting of glycine, N-acetylneuraminic acid and N-acetylgalactosamine … It is used as an alternate to [DB00019] for prophylactic use in cancer patients receiving chemotherapy and at risk for developing chemotherapy-induced neutropenia.
Products: LONQUEX SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 6MG/0.6MLRemifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. … Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Categories: Heterocyclic Compounds, 1-RingProducts: REMIFENTANILO 2 MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE, REMIFENTANILO 2MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE O INFUSION INTRAVENOSABenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]
Mixtures: CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant, Burn O Sol SprayCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesDNA gyrase subunit A
go.drugbank.com/bio_entities/BE0000366TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. … Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Polypeptides: DNA gyrase subunit ALeukotriene A-4 hydrolase
go.drugbank.com/bio_entities/BE0001680TargetHumansCan utilize LTA5 less effectively as a substrate than LTA4, and produce LTB5 (PubMed:2996528). … (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL) (PubMed:20813919, PubMed:24591641).
Polypeptides: Leukotriene A-4 hydrolaseSynonyms: Leukotriene A(4) hydrolaseAcetyl-coenzyme A synthetase
go.drugbank.com/bio_entities/BE0001916TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. … In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
Polypeptides: Acetyl-coenzyme A synthetaseNucleoside diphosphate kinase A
go.drugbank.com/bio_entities/BE0003106TargetEnzymeHumansMay also function as a Mg(2+)-dependent 3'-5' DNA exonuclease, excising nucleotides from 3' single-stranded DNA or DNA with 3' single strand overhangs, suggesting a role in DNA nucleolytic processing ( … Catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving a phosphohistidine intermediate, therefore
Polypeptides: Nucleoside diphosphate kinase ASynonyms: NDPK A, NDP kinase A