Search
Interleukin-12 receptor subunit beta-2
go.drugbank.com/bio_entities/BE0018860TargetHumansReceptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells.
Polypeptides: Interleukin-12 receptor subunit beta-2Synonyms: IL-12 receptor subunit beta-2Taste receptor type 2 member 10
go.drugbank.com/bio_entities/BE0020463TargetHumansGustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.
Polypeptides: Taste receptor type 2 member 10Synonyms: Taste receptor family B member 2Short transient receptor potential channel 4
go.drugbank.com/bio_entities/BE0020751TargetHumansForms a receptor-activated non-selective calcium permeant cation channel (PubMed:11042129, PubMed:11713258, PubMed:16144838, PubMed:39478185).
Polypeptides: Short transient receptor potential channel 4Short transient receptor potential channel 5
go.drugbank.com/bio_entities/BE0021113TargetHumansForms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991).
Polypeptides: Short transient receptor potential channel 5Synonyms: Transient receptor protein 5Taste receptor type 2 member 14
go.drugbank.com/bio_entities/BE0023216TargetHumansGustducin-linked G protein-coupled receptor that plays a role in the perception of bitterness (PubMed:38600377, PubMed:38776963). … The activity of this receptor stimulates GNAT3, activating the gustducin G protein pathway (PubMed:38600377, PubMed:38776963).
Polypeptides: Taste receptor type 2 member 14Synonyms: Taste receptor family B member 1Fidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigational[L49469] This approval was based on positive results demonstrated in the open-label, single-arm Phase 3 BENEGENE-2 study, where the annualized bleeding rate (ABR) was observed to be 1.3 for the 12 months … from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period.
Valbenazine
go.drugbank.com/drugs/DB11915ApprovedInvestigationalThis approval was supported by positive results in multiple trials, including the KINECT-HD Phase 3 study and the ongoing KINECT-HD2 open-label extension trial. … [L47885,A261135] Tardive dyskinesia has long been regarded as a consequence of anti-dopamine receptor therapy, and until 2008 with the advent of [tetrabenazine], most treatments were ineffective.
Bosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalThis approval was based on favorable results obtained from the open-label, randomized, multicenter trial BFORE that showed a significant improvement in major molecular response, defined as a ≤0.1% BCR … Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.
Fish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalRegardless, the specific mechanisms of action for these effects have yet to be formally elucidated. … In general, dietary or pharmaceutical intake of these acids is primarily the only way to increase their levels in the human body where they are overall an essential element to dietary health as they have
Mixtures: TL-Care DHA, TL-Select DHANorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalNorethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. … [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol
Mixtures: Feirza 1.5/30 Tm, Tilia FeCategories: Sex Hormones and Modulators of the Genital System