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Displaying results 1111 - 1120 of 10000 in total
  1. Drug

    Nilutamide

    go.drugbank.com/drugs/DB00665
    ApprovedInvestigational

    Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of normal and malignant prostatic tissue. … Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer.

    Categories: Antiandrogens, non-steroidal
  2. Drug

    Povidone

    go.drugbank.com/drugs/DB11061
    ApprovedInvestigationalWithdrawn

    The clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with … The FDA withdrew its approval for the use of all intravenous drug products containing povidone.[L43942] Other formulations of povidone continue to be available.

    Mixtures: DG Health Sterile Advanced Relief Eye, DG Health Advanced Relief Eye DropsCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

    Synonyms: 5-Fluoro-2,1-benzoxaborol-1(3H)-ol
  4. Drug

    Pascopyrum smithii pollen

    go.drugbank.com/drugs/DB10719
    Approved

    Pascopyrum smithii pollen is the pollen of the Pascopyrum smithii plant. Pascopyrum smithii pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic Extract
  5. Drug

    Magnesium ascorbate

    go.drugbank.com/drugs/DB14484
    ApprovedNutraceutical

    Mixtures: OB Complete GoldCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Dextroamphetamine

    go.drugbank.com/drugs/DB01576
    ApprovedIllicitInvestigational

    Dextroamphetamine is the dextrorotatory enantiomer of amphetamine[A2505]. Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder.[L6010,L52145]

    Mixtures: Mixed Salts of a Single-Entity Amphetamine Product, Mixed Salts of a Single-Entity Amphetamine ProductCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Drug

    Samidorphan

    go.drugbank.com/drugs/DB12543
    ApprovedInvestigational

    [A235638, A235643] Samidorphan was first approved as a variety of fixed-dose combination tablets with [olanzapine] by the FDA on May 28, 2021, and is currently marketed under the trademark LYBALVI™ … [Olanzapine] is an effective atypical antipsychotic that, like other antipsychotics, is associated with weight gain, metabolic dysfunction, and increased risk of type II diabetes.

    Categories: Heterocyclic Compounds with 4 or More Rings
  8. Drug

    Propiolactone

    go.drugbank.com/drugs/DB09348
    ApprovedWithdrawn

    Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. … [A32144] It is currently FDA approved for its use as an indirect additive used in food contact substances. Propiolactone was first commercially available in the United States in 1958.[A32144]

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Doravirine

    go.drugbank.com/drugs/DB12301
    ApprovedInvestigational

    treatments available for the management of HIV-1 infection. … [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg).

    Categories: Antivirals used in combination for the treatment of HIV infections, Non-Nucleoside Reverse Transcriptase Inhibitors
  10. Drug

    Bepotastine

    go.drugbank.com/drugs/DB04890
    Approved

    Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. … Bepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the