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Niraparib
go.drugbank.com/drugs/DB11793ApprovedInvestigationalNiraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. … [L43747] On December 12, 2025, the FDA expanded niraparib and abiraterone acetate (AKEEGA) with prednisone for the treatment of patients with BRCA2-mutated metastatic castration-sensitive prostate cancer
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersOctisalate
go.drugbank.com/drugs/DB11062ApprovedIt is an ester of salicylic acid and 2-ethylhexanol. … Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen.
Mixtures: It Radiant Multiple Cc for Man, Cactus Whitening Sun SPF 34 Pa Plus Plus for MenBlack cohosh
go.drugbank.com/drugs/DB13975Approved[A32543] The American College of Obstetrics and Gynecology guidelines on the use of botanicals, such as black cohosh, for the management of menopausal symptoms the use of for up to six months, especially … Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. Black cohosh has a long history of use.
Mixtures: Menopause Relief for WomenCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsZinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: OMEGA PLUS EMULSION FOR INFUSION, OMEGA SPECIAL EMULSION FOR INFUSIONCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigationalPremature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung development and may eventually cause asthma or early onset emphysema in those born prematurely. … [T716] The caffeine citrate injection, used for apnea of the premature newborn, was initially approved by the FDA in 1999.
Mixtures: PAT PO TJIN TJU SAN, Cold Remedy Gan Mao LingCategories: Tests for Gastric Secretion, Drugs for Obstructive Airway DiseasesAlpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigational[A179209] Approved by the FDA in May 2019, alpelisib is the first approved PI3K inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)- … Alpelisib was granted FDA approval on 24 May 2019.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.
Categories: Hormonal Contraceptives for Systemic Use, P-glycoprotein inducersProducts: Utrogestan Luteal 200 mg Weichkapseln zur vaginalen AnwendungTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalIt is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691].
Categories: Drugs for Functional Gastrointestinal Disorders, Cytochrome P-450 SubstratesProducts: DEBRIDAT FOR ORAL SUSPENSIONLNS-8801
go.drugbank.com/drugs/DB18091InvestigationalSynonyms: G 1 (g protein-coupled estrogen receptor agonist)Serine
go.drugbank.com/drugs/DB00133ApprovedInvestigationalNutraceuticalA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Mixtures: Aminosyn-PF, Aminosyn-PF