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Octreotide
go.drugbank.com/drugs/DB00104ApprovedInvestigational[L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. … Acromegaly is a life-threatening disease requiring life-long management.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze, Siroctid 0,5 mg/ml Injektionslösung in einer FertigspritzeEndoscopic Diagnosis in Esophagus
go.drugbank.com/conditions/DBCOND0084643Drugs: RanitidineSynonyms: Endoscopic Diagnosis in EsophagusBleeding in invasive procedures
go.drugbank.com/conditions/DBCOND0106041Drugs: LusutrombopagSynonyms: Bleeding in invasive proceduresMutation in SMN1 gene
go.drugbank.com/conditions/DBCOND0173803Drugs: Onasemnogene abeparvovecSynonyms: Mutation in SMN1 geneHuman C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigational[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several soft tissues or edema, which may last up to five days when untreated.[L16586, L16606]
Categories: Drugs Used in Hereditary AngioedemaSynonyms: C1-INHHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … It is used in industrial and cosmetic applications as a bleaching agent.
Mixtures: Prevention Wound and Burn, BANEN Rinse-free Hand Sanitizer (II)Categories: Compounds used in a research, industrial, or household settingRemifentanil
go.drugbank.com/drugs/DB00899ApprovedInvestigationalRemifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. … Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Categories: Heterocyclic Compounds, 1-RingProducts: REMIFENTANILO 2 MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE, REMIFENTANILO 2MG POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE O INFUSION INTRAVENOSADNA gyrase subunit A
go.drugbank.com/bio_entities/BE0000366TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. … Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
Polypeptides: DNA gyrase subunit ALeukotriene A-4 hydrolase
go.drugbank.com/bio_entities/BE0001680TargetHumansCan utilize LTA5 less effectively as a substrate than LTA4, and produce LTB5 (PubMed:2996528). … (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL) (PubMed:20813919, PubMed:24591641).
Polypeptides: Leukotriene A-4 hydrolaseSynonyms: Leukotriene A(4) hydrolaseAcetyl-coenzyme A synthetase
go.drugbank.com/bio_entities/BE0001916TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. … In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
Polypeptides: Acetyl-coenzyme A synthetase