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Displaying results 1121 - 1130 of 3387 in total
  1. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyproge...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Inducers
  2. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    [A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due to the presence of multiple adverse effects and warnings regarding their use (e.g. congestive heart … and [troglitazone], exerts its pharmacological effect primarily by promoting insulin sensitivity and the improved uptake of blood glucose[L11416] via agonism at the peroxisome proliferator-activated receptor-gamma

    Mixtures: INCRESINA PCategories: Peroxisome Proliferator Receptor gamma Agonist, Peroxisome Proliferator-activated Receptor Activity
  3. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Fluciclovine (18F)

    go.drugbank.com/drugs/DB13146
    ApprovedInvestigational

    Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by t...

  5. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, t...

    Mixtures: Germa TanProducts: PF Anti Bac
  6. Target

    G protein-coupled receptor family C group 5 member D

    go.drugbank.com/bio_entities/BE0010290
    TargetHumans

    G protein-coupled receptor involved in hard keratin expression and likely plays a role in the development of hair and nails

    Polypeptides: G protein-coupled receptor family C group 5 member DFunction: G protein-coupled receptor activity
  7. Drug

    Azintuxizumab vedotin

    go.drugbank.com/drugs/DB14847
    Investigational

    investigation in clinical trial NCT02951117 (A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent

  8. Drug

    Cytisine

    go.drugbank.com/drugs/DB09028
    Investigational

    Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. … Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.

  9. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: Aminosyn-PF, Aminosyn-PF
  10. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    In June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S.

    Categories: Estrogen Receptor Modulators