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Displaying results 1131 - 1140 of 10000 in total
  1. Drug

    Botulinum toxin type A

    go.drugbank.com/drugs/DB00083
    ApprovedInvestigational

    , and hyperhidrosis. … [A231824] With a wide variety of applications and favourable safety profile, Botulinum toxin A injection is a minimally invasive and promising treatment for cosmetic imperfections, muscle spasms, and other

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsProducts: BOTOX®200 U, NEURONOX ®50 U
  2. Drug

    Proguanil

    go.drugbank.com/drugs/DB01131
    Approved

    Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells. … It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.

    Mixtures: Atovaquone and Proguanil HCl, Atovaquone and Proguanil HClCategories: proguanil and atovaquone, chloroquine and proguanil
  3. Drug

    Frovatriptan

    go.drugbank.com/drugs/DB00998
    Approved

    Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. … Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.

    Categories: Serotonin-1b and Serotonin-1d Receptor AgonistProducts: TIGREAT 2.5MG, EUMITAN 2.5MG FTA
  4. Drug

    Trametinib

    go.drugbank.com/drugs/DB08911
    ApprovedInvestigational

    [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.

    Categories: Antineoplastic and Immunomodulating Agents, Genito Urinary System and Sex HormonesProducts: MEKINIST FILM-COATED TABLETS 2MG, Meqsel 2mg Film-Coated Tablet
  5. Indication

    Minor aches and pains

    go.drugbank.com/conditions/DBCOND0118556
    Drugs: Acetaminophen · Choline salicylate · Eucalyptus oil · Guaifenesin · Ibuprofen · Phenylephrine +3 more
    Synonyms: Minor aches and pains
  6. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    [A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical … [A191379, A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action,[A222398] and to date, it has demonstrated _in vitro_ activity against the _Arenaviridae_, _Flaviviridae

    Categories: Amino Acids, Peptides, and Proteins, Nucleosides and NucleotidesProducts: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL
  7. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. … Meloxicam is available in oral, transdermal, and intravenous formulations.

    Categories: bupivacaine and meloxicam, Antiinflammatory and Antirheumatic ProductsProducts: MELOFLAMIN MK 7.5 MG CÁPSULAS, MEXIMED®15MG
  8. Target

    B- and T-lymphocyte attenuator

    go.drugbank.com/bio_entities/BE0010629
    TargetHumans

    Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). … In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state.

    Polypeptides: B- and T-lymphocyte attenuatorSynonyms: B- and T-lymphocyte-associated protein
  9. Drug

    Diamorphine

    go.drugbank.com/drugs/DB01452
    ApprovedIllicit

    As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom. … Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single Convention on Narcotic Drugs.

    Products: Diamorphine Hydrochloride Inj 100mg/ml BP, Diamorphine Hydrochloride Inj 30mg/ml BP
  10. Drug

    Sirolimus

    go.drugbank.com/drugs/DB00877
    ApprovedInvestigational

    [A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in patients aged 13 years and older receiving renal transplants. … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island

    Categories: Sirolimus and Prodrugs, Antineoplastic and Immunomodulating AgentsProducts: RAPAMUNE TABLET 1MG, RAPAMUNE TABLETS (1MG)