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Chlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnIt belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-(p-chlorobenzenesulfonyl)-3-propylurea, 1-(p-chlorophenylsulfonyl)-3-propylureaFluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalA phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal … It has been approved by FDA for use in externally applied drugs and cosmetics. (From Merck Index, 12th ed; American Medical Association Drug Evaluations; 1995, p2275)
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingSynonyms: Japan Yellow 201, D&C Yellow No. 7Meperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ALDOLAN 100 MG/2 ML AMPUL, 5 ADET, PETHOLAN 100 MG/2 ML ENJEKSIYONLUK ÇÖZELTI, 5 ADETNateglinide
go.drugbank.com/drugs/DB00731ApprovedApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADET, NAT-ALA 180/200 MG FILM KAPLI TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalA non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. … Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or
Categories: P-glycoprotein substratesProducts: BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE, BLOK-L 10 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADETIodine I-131 monoclonal antibody 81C6
go.drugbank.com/drugs/DB16197InvestigationalNeuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).
Synonyms: 81c6, a murine igg2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), Anti-tenascin 81C6 monoclonal antibody labeled w/ I 131Calcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalThe best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. … The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions.
Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, Calcium With Vitamin D 200 Mg/160 IuCategories: ascorbic acid (vit C) and calciumRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Ernevod 100 mg Film Kaplı Tablet (12 adet), EVRENZO 100 MG FİLM KAPLI TABLET, 12 ADETUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ZYDENA 100 MG FILM TABLET, 2 ADET, ZYDENA 100 MG FILM TABLET, 4 ADETIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: D-Isosorbide dinitrate