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Protein S100-A12
go.drugbank.com/bio_entities/BE0001206TargetHumansS100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.
Synonyms: Calcium-binding protein in amniotic fluid 1Lisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigational[A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.
Categories: Compounds used in a research, industrial, or household setting, Agents Acting on the Renin-Angiotensin SystemSynonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-prolinePectin
go.drugbank.com/drugs/DB11158ApprovedInvestigationalVet approvedPectin is a heteropolysaccharide commercially derived from the cell wall of higher plants.[A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. … [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or as acid amides.
Categories: Compounds used in a research, industrial, or household settingPadimate O
go.drugbank.com/drugs/DB11570ApprovedPadimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic effects on yeast i_n vivo_ [A32458].
Mixtures: Lip Smacker SPF Cherry Berry Ball, Skin Pro-tec II SPF-15Categories: Compounds used in a research, industrial, or household settingFluoroestradiol F-18
go.drugbank.com/drugs/DB15690ApprovedInvestigational[L14117] It is expected to be available in late 2020/early 2021.[L14117] … [L14096] The ability to image ER-positive tumors _in vivo_ is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression
Ropeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models and clinical trials. … [A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients.
Synonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bCategories: Interferon Type IBiotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Doll Lash, Insur-all Vitamin SupplementProducts: BIO-H-TIN Vitamin H 5 mg - Tabletten, BIO-H-TIN Vitamin H 2,5 mg - TablettenLonapegsomatropin
go.drugbank.com/drugs/DB16220ApprovedInvestigational[L36380,L10971] Lonapegsomatropin was granted FDA approval on 25 August 2021.[L36380] It was later approved by the European Commission on 13 January 2022.[L39900] … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least
Pirtobrutinib
go.drugbank.com/drugs/DB17472ApprovedInvestigational[A256788] In January 2023, the use of pirtobrutinib for the treatment of relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy was approved under the FDA's Accelerated … in the presence of Cys481 mutations.
Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalan important role in tumor cell growth and survival. … of cell growth in tumors that overexpress Trk.