Padimate O is an ingredient used in sunscreens to absorb UV radiation. Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA.
- Mechanism
- Curator reviewed · 1 reference
It is proposed that simultaneous contact of padimate O with keratinocytes can stimulate the diffusion through human epidermis. Upon photoexcitation, padimate O generates singlet oxygen and forms carbon-centred free radicals. While padimate O attenuates simple and repairable, UV-induced cellular damage, it may also increase complex chemical damage that is more difficult to repair by normal cells.
- Primary indication
- Indicated as an active UV-B filter to prevent photodamage.Curator reviewed
- Formula / weight
- C17H27NO2 · 277.408 g/mol (avg)
- First approval
- Canada, 1997
- Also known as
- Padimate-O
Resolves to
WYWZRNAHINYAEF-UHFFFAOYSA-NSMILESCCCCC(CC)COC(=O)C1=CC=C(C=C1)N(C)CWhat you can answer from here — as of May 03, 2025
Which companies are running trials of Padimate O, in which indications and phases, and which of those programs are still active?
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