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Vemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche. … [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: ZELBORAF 240 MG FILM KAPLI TABLET ,56 FILM KAPLI TABLET, ZELBORAF ® TABLETAS LACADAS DE 240 MGCefalotin
go.drugbank.com/drugs/DB00456ApprovedVet approvedWithdrawnCefalotin is a cephalosporin antibiotic.
Categories: Heterocyclic Compounds, 2-RingSynonyms: CET, 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acidInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Compared to available long-acting analogs such as [DB00047] and [DB01307], which have a duration of action of 20-24 hours, insulin degludec provides a consistent level … Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 10 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalIt is used extensively as an antiviral or antineoplastic agent. … Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23.
Synonyms: IFN alpha-2B, rIFN-alpha-2bMixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)Chlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: LIBKOL FILM TABLET, 20 TABLET, LIBRAX DRAJE, 100 ADETCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigational[A203111] Pamidronic acid was first described in the literature in 1977. … [A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]
Products: AREDIA 90 MG/10 ML FLAKON, 1 ADET, PAMISOL CONCENTRATED INJECTION 90 mg/10 mlFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Synonyms: 5-FC, 5-FluorocytosineProducts: FLUSYNERG® 10 MG/ML SOLUCIÓN INYECTABLE, โทซีน (500 มก.แคปซูล)Ritodrine
go.drugbank.com/drugs/DB00867ApprovedWithdrawnAdrenergic beta-agonist used to control premature labor.
Categories: Adrenergic beta-2 Receptor AgonistsProducts: PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPULSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigational[A218551] Some of the pro-inflammatory mechanisms involved in NMOSD are thought to be mediated, at least in part, by IL-6, including increased production of anti-aquaporin-4 (AQP4) autoantibodies and increased … a pH-dependent manner[A218551] - this allows satralizumab to bind an IL-6 receptor until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to
Products: ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe, ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigational(Merck, 11th ed.)
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: VINCABLAS® 10 MG/VIAL, VINBLASTINA SULFATO 10 MG