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Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. … It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Xylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnNevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes. … The dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar in living things. The levorotary form, L-xylose, can refer to the form that is synthesized.
Synonyms: D-Xylose, aldehydo-D-xyloseMoxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approvedIt was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of the milbemycin class. … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side chain at carbon 25 and a unique methoxime moiety at carbon 23.
Mixtures: Advocate Spot-on Solution for Small Dogs, Advocate Spot-on Solution for Large DogsCategories: Compounds used in a research, industrial, or household settingAvalglucosidase alfa
go.drugbank.com/drugs/DB16099ApprovedInvestigational[A232960] On August 6, 2021, avalglucosidase alfa-ngpt was approved by the FDA under the market name Nexviazyme to treat patients one year of age and older with late-onset Pompe disease. … [L35160] Avalglucosidase alfa was approved by Health Canada on November 15, 2021 for the treatment of patients older than six months of age with late-onset Pompe disease.
Synonyms: Neo-recombinant human acid alpha-glucosidaseNepafenac
go.drugbank.com/drugs/DB06802ApprovedInvestigationalNepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Categories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs), Anti-Inflammatory Agents, Non-Steroidal (Non-Selective)Synonyms: 2-amino-3-benzoylbenzeneacetamideBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approved[A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
Mixtures: Throwers Pbc No. 1, TUDERM-NCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesEstriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedIt is however available in the United States by prescription filled only by compounding pharmacies. … Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.
International brands: Synapause EMixtures: HelloPharmacist Bi-EST 5.0 Cream, GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETCultivated mushroom
go.drugbank.com/drugs/DB10544ApprovedCultivated mushroom allergenic extract is used in allergenic testing.
Synonyms: Agaricus bisporus (mushroom) cap/stem extractCategories: Non-Standardized Food Allergenic ExtractBulevirtide
go.drugbank.com/drugs/DB15248ApprovedInvestigational[A226305] Bulevirtide, also known as Hepcludex, is a first-in-class entry inhibitor for the treatment of chronic Hepatitis D infection developed by MYR Pharmaceuticals, now part of Gilead. … It was first approved for use in the EU on May 28, 2020; bulevirtide has been granted PRIME scheme eligibility and Orphan Drug Designation by the European Medicines Agency.
International brands: Myrcludex BRemoxipride
go.drugbank.com/drugs/DB00409ApprovedWithdrawn[A215422] It gained approval in the UK in 1989 but was withdrawn in 1993 after it was found to be associated with an increased incidence of aplastic anemia.[A215422,A215512] … Remoxipride is an atypical antipsychotic agent that is specific for dopamine D<sub>2</sub> receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors