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Displaying results 1151 - 1160 of 2828 in total
  1. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...

  2. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenz...

    Mixtures: Se-Natal 19, Se-Natal OneCategories: Vitamin B Complex
  3. Drug

    Picolinic acid

    go.drugbank.com/drugs/DB05483
    Experimental

    PCL-016 plays a key role in zinc transport.

  4. Drug

    Corifollitropin alfa

    go.drugbank.com/drugs/DB09066
    ApprovedInvestigational

    In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. FDA for its New Drug Application for this drug.

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  5. Drug

    Sodium borate

    go.drugbank.com/drugs/DB14505
    Approved

    Mixtures: Sel De Perou
  6. Drug

    Coal tar

    go.drugbank.com/drugs/DB11082
    Approved

    Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.

    Mixtures: X-seb T Shampoo, X-seb T Plus Conditioning ShampooCategories: Complex Mixtures
  7. Drug

    Nafcillin

    go.drugbank.com/drugs/DB00607
    ApprovedInvestigational

    A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug.

  8. Target

    P-type sodium-transporting ATPase4

    go.drugbank.com/bio_entities/BE0009185
    TargetPlasmodium falciparum (isolate 3D7)

    Sodium-exporting ATPase (PubMed:23414762, PubMed:29986883, PubMed:31311978, PubMed:36180431). Required for the extrusion of Na(+) from the intraerythrocytic parasites to maintain a low cytosolic concentration of Na(+) (PubMed:23414762, P...

    Synonyms: P-type cation-transporter ATPase4Function: ABC-type sodium transporter activity
  9. Drug

    Ezogabine

    go.drugbank.com/drugs/DB04953
    ApprovedWithdrawn

    Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase ...

    Categories: Membrane Transport Modulators
  10. Target

    N-lysine methyltransferase KMT5A

    go.drugbank.com/bio_entities/BE0019990
    TargetHumans

    Nucleosomes are preferred as substrate compared to free histones (PubMed:12086618, PubMed:12121615, PubMed:15200950, PubMed:15933069, PubMed:15933070, PubMed:15964846, PubMed:16517599).

    Synonyms: SET domain-containing protein 8, PR/SET domain-containing protein 07