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Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigational[A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308]
Products: VELGASTIN BLAEHUNGEN SUSPasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalIt is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Nitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalNitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning.
Calcium levulinate
go.drugbank.com/drugs/DB13800ApprovedThe resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in calcium lactate … This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and soy products with calcium
Mitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalwell as adjunctly to _ab externo_ glaucoma surgeries. … has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract Urothelial Cancer (LG-UTUC)[L12867] - as
Glyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigationalGlyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin se...
Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription
Mixtures: PERINDOPRIL E INDAPAMIDE MYLAN GENERICS, PERINDOPRIL E INDAPAMIDE MYLAN GENERICSProducts: INDAPAMIDE DOC GENERICI, INDAPAMIDE MYLAN GENERICSPanthenol
go.drugbank.com/drugs/DB11204ApprovedFurthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties [A32377]. … Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol).
Asparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalIt is available as intramuscular or intravenous injections. … L-asparaginase of _E. coli_ is marketed under several different trade names, including Elspar, for the treatment of acute lymphoblastic leukemia (ALL) as part of a multi-agent chemotherapeutic regimen.
Ammonia
go.drugbank.com/drugs/DB11118ApprovedInvestigationalAlthough ammonia is used as a food additive in the anhydrous form and serves as a starting material in pharmaceutical and commercial products, it is caustic and hazardous when concentrated. … Ammonia gas has been used in the clinical setting as a respiratory stimulant to prevent fainting.