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Fondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII).
Categories: Factor Xa Inhibitors, Indirect factor Xa inhibitorsProducts: ARIXTRA 12.5MG/ML SOLUTION FOR INJECTION, ARIXTRA 2.5MG/0.5ML SOLUTION FOR INJECTIONSugammadex
go.drugbank.com/drugs/DB06206ApprovedInvestigationalSugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. … patients may require for surgery.
Categories: Compounds used in a research, industrial, or household settingProducts: BRIDION 100MG/ML SOLUTION FOR INJECTION, Bridion Solution For Injection 100mg/mlCiltacabtagene autoleucel
go.drugbank.com/drugs/DB16738ApprovedInvestigational[L40749] There have been a number of treatments developed for multiple myeloma (e.g. [daratumumab]), although none are curative. … [A245854] B-cell maturation antigen (BCMA) is a transmembrane glycoprotein member of the tumor necrosis factor receptor superfamily 17 (TNFRSF17) which is used as a biomarker for multiple myeloma.
Ethiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: Compounds used in a research, industrial, or household settingVismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigational[A258613,A258618,L45803] It was discovered by high-throughput screening of a library of small-molecule compounds and subsequent optimization through medicinal chemistry. … Afterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells.
Sotrovimab
go.drugbank.com/drugs/DB16355ApprovedInvestigational[L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising COVID-19 cases caused by the Omicron BA.2 sub-variant, where the drug is ineffective. … found to reduce the risk of death or hospitalization in high-risk adults with COVID-19 in the outpatient setting.
Categories: Antiinfectives for Systemic Use, Approved Treatments for COVID-19Products: Sotrovimab for InjectionChlorquinaldol
go.drugbank.com/drugs/DB13306ApprovedChlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of bacterial vaginosis.[F4552] … Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan.
Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … relief was observed to be 8 hours compared to 36 hours for the placebo treatment.
Zanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigationaltrial whose tumour is entirely or partially destroyed by a drug. … [L10163] Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early relapse, poor clinical outcomes, and long-term survival.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexChlordiazepoxide
go.drugbank.com/drugs/DB00475ApprovedIllicitAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Mixtures: Pro Chlorax, AA PHARMA CHLORAX CAPSULE