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Oteseconazole
go.drugbank.com/drugs/DB13055ApprovedInvestigational[A247050] The use of oteseconazole is contraindicated in females of reproductive potential due to its embryo-fetal toxicity risks.[L41635] This drug was approved by the FDA on April 26, 2022. … Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseMenotropins
go.drugbank.com/drugs/DB00032ApprovedInvestigationalIt is used as a fertility medication that is injected either subcutaneously or intramuscularly. … It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed by the US approval in October, 2018. … Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseHolcus lanatus pollen
go.drugbank.com/drugs/DB10395ApprovedHolcus lanatus pollen is the pollen of the Holcus lanatus plant. Holcus lanatus pollen is mainly used in allergenic testing.
Mixtures: Treatment Set TS333938, Treatment Set TS128872Arrhenatherum elatius pollen
go.drugbank.com/drugs/DB10879ApprovedArrhenatherum elatius pollen is the pollen of the Arrhenatherum elatius plant. Arrhenatherum elatius pollen is mainly used in allergenic testing.
Mixtures: Treatment Set TS333938, Treatment Set TS128872Pretomanid
go.drugbank.com/drugs/DB05154ApprovedInvestigational[A182915] Pretomanid is an antimycobacterial agent that is administered with [Bedaquiline] and [Linezolid] to treat resistant forms of pulmonary TB. … It was the first TB drug developed by a nonprofit organization, known as TB Alliance, and was granted FDA approval on August 14, 2019.
Categories: Antiinfectives for Systemic UseFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Synonyms: (1R,2S,8S,10S,11S,14R,15S,17S)-14-acetyl-1-fluoro-14,17-dihydroxy-2,8,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-oneMixtures: FML-S, FML-neo Oph SusElafibranor
go.drugbank.com/drugs/DB05187ApprovedInvestigationalElafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist [A263833] that works to inhibit bile acid synthesis.
Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalNovember 2013 for the treatment of mantle cell lymphoma (MCL) under accelerated approval;[L12228] however, in April 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.
Cladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell … Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes.
Synonyms: (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol