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Satralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigational[A218551] Some of the pro-inflammatory mechanisms involved in NMOSD are thought to be mediated, at least in part, by IL-6, including increased production of anti-aquaporin-4 (AQP4) autoantibodies and increased … a pH-dependent manner[A218551] - this allows satralizumab to bind an IL-6 receptor until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to
Products: ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe, ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedIt is also used as a mild laxative for human or veterinary uses. … Mineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and prevent dry, rough, scaly, itchy skin and minor skin irritations.
Mixtures: retaine MGD, AGAROL M (EMULSION)Products: Truffle EX Cleansing, LIQUID PARAFFIN EMULSION 2.5 ml/5 mlUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena. … It is not yet approved for use in the U.S., E.U., or Canada.
Categories: Drugs Used in Erectile Dysfunction, Phosphodiesterase 5 InhibitorsProducts: ZYDENA 100 MG FILM TABLET, 2 ADET, ZYDENA 100 MG FILM TABLET, 4 ADETNadolol
go.drugbank.com/drugs/DB01203ApprovedInvestigational[A34177] Nadolol was granted FDA approval on 10 December 1979.[L7922] … [L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and
Mixtures: CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MGCategories: MATE 2 Substrates, Cytochrome P-450 SubstratesMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigational[A242557] Maribavir is novel in that it instead targets the CMV pUL97 kinase, thereby providing an effective alternative treatment option in cases of resistant infections. … Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet), Livtencity 200 mg Film Kaplı Tablet (28 Adet)Bismuth subsalicylate
go.drugbank.com/drugs/DB01294ApprovedVet approved[A230733] Bismuth subsalicylate has been around for over 100 years: it was originally developed in 1901 for hygienic use and sanitation for cholera infection. … Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight.
Synonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-oneProducts: BİZMOPEPTOL MAX 1050 MG/30 ML ORAL SÜSPANSİYON, 240 ML, BİZMOPEPTOL 525 MG/30 ML ORAL SÜSPANSİYON , 240 MLPilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigational[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors.
Mixtures: E-pilo-2 Oph Soln, E-pilo 2 Ophthalmic SolutionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsTetryzoline
go.drugbank.com/drugs/DB06764Approved[L32579] Tetryzoline is also found in combination products with other lubricants and anti-irritants, such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. … [L32584, L32589, L32594] It is also used in combination with other drug classes, such as antihistamines, corticosteroids, and glucocorticoids in other countries.
Mixtures: EFEMOLINE 5 ML DAMLA, OCTILIA ALLERGIA E INFIAMMAZIONECategories: Compounds used in a research, industrial, or household settingPentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEProducts: ELMIRON 100 MG KAPSÜL, 100 ADET, Elmidam 100 mg Sert Kapsül, 100 ADETChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine]. … Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine