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Displaying results 1171 - 1180 of 7283 in total
  1. Drug

    Sodium feredetate

    go.drugbank.com/drugs/DB13381
    Approved

    Synonyms: Feredato de sodio, Ferédétate de sodiumMixtures: Bal-Care DHA, Cavan-EC SOD DHA
  2. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

    Mixtures: BumP DHA, BumP DHACategories: Vitamin B Complex
  3. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. … [A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and

    Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE., DOXORUBICINA CLORHIDRATO POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE X 50 MG
  4. Drug

    Erdafitinib

    go.drugbank.com/drugs/DB12147
    ApprovedInvestigational

    tool kit to treat such a prevalent medical condition. … [L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index
  5. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Moxifloxacin is a synthetic fluoroquinolone antibiotic agent.

    Mixtures: MOFLAG D, MOFLAG DProducts: MOXIFLOXACIN 1A PHAR 400MG, Moxifloxacin 1A Pharma 400 mg - Filmtabletten
  6. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    [A264289] It was approved by the FDA on August 19, 2024.[L51189] Lazertinib is used alone or in combination with other chemotherapeutic agents.[L51184]

  7. Drug

    DAR-0100A

    go.drugbank.com/drugs/DB16139
    Investigational

    DAR-0100A is under investigation in clinical trial NCT01466205 (Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder).

    Categories: Dopamine D1 Receptor Agonists
  8. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    leading to DNA lesions and eventual apoptosis. … Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to

    Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one, 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
  9. Drug

    Idoxuridine

    go.drugbank.com/drugs/DB00249
    ApprovedWithdrawn

    An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.

    Synonyms: 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil, 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracilProducts: Herplex D
  10. Drug

    Disopyramide

    go.drugbank.com/drugs/DB00280
    ApprovedInvestigational

    A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar

    Categories: Antiarrhythmics, Class IaProducts: Rythmodan-LA, Rythmodan-LA 250mg