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Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigationalSimethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in ...
Mixtures: MAAG GEL, PRIMPERAN GELPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedPotassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent.
Estradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedFirst-pass metabolism by the gut and the liver quickly degrades the estradiol molecule before it gets a chance to enter systemic circulation and exert its estrogenic effects [A12102].
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesEcallantide
go.drugbank.com/drugs/DB05311ApprovedEcallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema. Ecallantide is a recombinant 60-amino-acid protein produced in Pichia pastoris yeast cells ...
Thimerosal
go.drugbank.com/drugs/DB11590ApprovedThiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used...
Recombinant alpha 1-antitrypsin
go.drugbank.com/drugs/DB05481InvestigationalThe rAAT topical gel (Dermolastin™) is indicated for patients with atopic dermatitis and psoriasis.
Prilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: MAXTIME® GEL, MAXTIME® GELAtirmociclib
go.drugbank.com/drugs/DB21733InvestigationalAtirmociclib is under investigation in clinical trial NCT06760637 (Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment
Caffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigationalCaffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophy...
Mixtures: YINCHI BRAND FEVER & COLD'S TABLETS, GelCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsL-arginine
go.drugbank.com/drugs/DB17289ApprovedInvestigationalNutraceuticalMixtures: Aminosyn-PF 7%, Aminosyn-PF 10%