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Carteolol Action Pathway
smpdb.ca/view/SMP0000658Drug actionCarteolol (also known as Cartrol or Ocupress) is a selective β1 adrenergic receptor antagonist (beta blocker), which can be used for treatment of high blood pressure (hypertension) and irregular heartbeats (arrhythmias). Carteolol a...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Dobutamine Action Pathway
smpdb.ca/view/SMP0000662Drug actionDobutamine is a type of medication that can be used for treating heart failure and cardiogenic shock. Dobutamine can bind to beta-1 adrenergic receptor on the heart cell which lead to mild chronotropic, arrhythmogenic, hypertensive and v...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Levobunolol Action Pathway
smpdb.ca/view/SMP0000666Drug actionLevobunolol (also known as Betagan) is an ophthalmic beta blocker (non-selective) that can produce cardiovascular effects and systemic pulmonary effects. Levobunolol bind to beta1-adrenergic and beta2-adrenergic receptors in heart and va...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Metipranolol Action Pathway
smpdb.ca/view/SMP0000667Drug actionMetipranolol (also known as Betanol or Disorat) is an beta blocker (non-selective) that can used as an antihypertensive, antiarrhythmic and antiglaucoma agent. Metipranolol binds to beta1-adrenergic and beta2-adrenergic receptors in hear...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Practolol Action Pathway
smpdb.ca/view/SMP0000669Drug actionPractolol (also known as Eraldin or Dalzic) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Practolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the bindin...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Amiodarone Action Pathway
smpdb.ca/view/SMP0000665Drug actionThe drug inhibits Na,K-activated myocardial adenosine triphosphatase, calcium and potassium channels and beta adrenergic receptors causing an increase in ventricular and atrial muscle action duration.
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Tocainide Sodium Channel Cardiac Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0126519Drug actionTocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells.
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Procainamide Action Pathway (New)
smpdb.ca/view/SMP0126265Drug actionProcainamide mainly inhibits sodium channels protein type 5 subunit alpha but also inhibits the potassium voltage gated channel subfamily H member 2.
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Atenolol Action Pathway
smpdb.ca/view/SMP0000298Drug actionAtenolol, trade name Tenormin, is a beta blocker prescribed to treat hypertension. Atenolol is a selective beta-1-adrenoceptor antagonist targeting the heart and vascular smooth muscle to inhibit sympathetic activity. Binding of atenolol...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Bisoprolol Action Pathway
smpdb.ca/view/SMP0000300Drug actionBisoprolol (also known as Zebeta) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to reduced heart ...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4