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Displaying results 111 - 120 of 4018 in total
  1. Drug

    Loxoprofen

    go.drugbank.com/drugs/DB09212
    ApprovedInvestigational

    Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug.

    Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDS
  2. Drug

    Resmetirom

    go.drugbank.com/drugs/DB12914
    ApprovedInvestigational

    On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD

  3. Target

    Bone marrow proteoglycan

    go.drugbank.com/bio_entities/BE0002114
    TargetHumans

    Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the...

    Polypeptides: Bone marrow proteoglycan
  4. Drug

    Ipilimumab

    go.drugbank.com/drugs/DB06186
    ApprovedInvestigational

    [L12126] Ipilimumab was granted FDA approval on 25 March 2011.[L12126]

  5. Target

    Bone morphogenetic protein 10

    go.drugbank.com/bio_entities/BE0010910
    TargetHumans

    Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors s...

    Polypeptides: Bone morphogenetic protein 10
  6. Target

    Forkhead box protein M1

    go.drugbank.com/bio_entities/BE0014280
    TargetHumans

    Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis (PubMed:19160488, PubMed:20360045). Plays a role in the control of cell proliferation (PubMed:19160488). Also plays a role in DN...

    Polypeptides: Forkhead box protein M1
  7. Indication

    Secondary Malignant Neoplasm of Bone

    go.drugbank.com/conditions/DBCOND0046703
    Drugs: Clodronic acid · Pamidronic acid
    Synonyms: Secondary malignant neoplasm of bone and bone marrow, Bone metastases
  8. Indication

    Bone Diseases, Infectious

    go.drugbank.com/conditions/DBCOND0076351
    Drugs: Cephalexin · Tobramycin
    Synonyms: Bone Infection, Infection in Bone
  9. Indication

    Severe Bone Resorption

    go.drugbank.com/conditions/DBCOND0134282
    Drugs: Cholecalciferol
    Synonyms: Severe Bone Resorption
  10. Drug

    Sevabertinib

    go.drugbank.com/drugs/DB21667
    ApprovedInvestigational

    Sevabertinib is a kinase inhibitor indicated for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) whose tumors have HER2 (ERBB2) tyrosine kinase domain … [L54638] Sevabertinib was granted accelerated approval by the FDA on November 19th, 2025 for patients who had received a prior systemic therapy.