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Carbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalof this ingredient as an oral wound healing agent [L1976]. … As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products.
Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[L41900] It is used as monotherapy or in combination with other drugs, such as corticosteroids. … [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017.
Ethylhexyl methoxycrylene
go.drugbank.com/drugs/DB11226ApprovedIt currently enjoys regional approvals in Canada, the EU, and the US [L2847]. … It is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various lotions, creams, sprays, sticks, and gel formulations [F104].
Lepirudin
go.drugbank.com/drugs/DB00001ApprovedWithdrawnLepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor. … [A246609] Lepirudin is used as an anticoagulant in patients with heparin-induced thrombocytopenia (HIT), an immune reaction associated with a high risk of thromboembolic complications.
Balsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approvedas safe (GRAS). … [F117] Under the FDA, balsam of Peru is considered as an inactive ingredient to be used for approved drug products[L2878] as well as an approved food additive under the categorization of generally recognized
Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase.
Rose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalRose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. … The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, breast cancer and skin conditions such as eczema and psoriasis are being investigated in clinical trials
Peppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalPeppermint oil is used as a flavouring agent in foods and fragrance in hygienic or cosmetic products, and as an anti-itch and cooling agent in topical pharmaceutical products. … Medicinal use of herbal ingredients such as peppermint oil has a long history of treating digestive disorders and upper respiratory symptoms and cough [A33055].
Mixtures: Naus-overPhenylbutyric acid
go.drugbank.com/drugs/DB06819ApprovedInvestigationalIt demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone.
Hydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing … It is used in industrial and cosmetic applications as a bleaching agent.