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Displaying results 111 - 120 of 47710 in total
  1. Drug

    Glycopyrronium

    go.drugbank.com/drugs/DB00986
    ApprovedInvestigationalVet approved

    [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers. … [A233565] Glycopyrronium was originally granted FDA approval on 11 August 1961.[L33090]

    Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, ULTIBRO BREEZHALER INHALATION POWDER HARD CAPSULE 110/50 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  2. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A797] Although oxaliplatin has been investigated as a monotherapy, it is typically administered in combination with fluorouracil and leucovorin, known as the FOLFOX regimen, for the treatment of colorectal … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.

    Products: OXALIPLATINO 50 MG / 10 ML, OXALITIN INJECTION 50 MG/10 ML
  3. Drug

    Calcium acetate

    go.drugbank.com/drugs/DB00258
    Approved

    It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.

    Mixtures: OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET, PROCALAMINE SISE 500 ML(SETLI)Products: FIX-AT 1000 MG SAŞE, 90 ADET, ANTI-FOSFAT CA 700 MG TABLET, 100 ADET
  4. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    Morphine was granted FDA approval in 1941.[L12114] … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.

    Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366]. … In 2010, it was estimated that 36 million people worldwide live with Alzheimer's Disease. In 2013, this number increased to 44 million.

    Synonyms: 1,3-Dimethyl-5-adamantanamineMixtures: MEGINGO 10/50 MG EFERVESAN TABLET, 100 ADET, MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADET
  6. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: Nucynta ER Tablets 100 mg, PALEXIS® RETARD 100 MG
  7. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.

    International brands: Theodur GMixtures: THEOLONG 1200/400 MG EFERVESAN TABLET, 10 ADET, THEOLONG 600/200 MG EFERVESAN TABLET, 10 ADET
  8. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    [L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: FENTANYL 0,05 MG/ML 10 ML SOLÜSYON İÇEREN IV AMPUL, 50 ADET, FENTANEST 500 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET)
  9. Drug

    Maridebart Cafraglutide

    go.drugbank.com/drugs/DB19339
    Investigational

    Maridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity

    Synonyms: gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-33*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, Immunoglobulin G1, anti-(glucose-dependent insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human γ1-chain), disulfide with human κ-chain, dimer, 275,275′-bis(
  10. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.

    Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsProducts: INVEGA HAFYERA 1000 mg/5.0 mL Prolonged-Release Suspension for Intramuscular Injection, @ctavis 50 mg Depot-Injektionssuspension