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Cyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedCyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: DNACIPOL-N, Cyclosporine/Chondroitin PFAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in move...
International brands: PK-MerzMixtures: FROSDEM-PHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 1...
Mixtures: DESYN-N, Ti-U-lac HC LotionCategories: P-glycoprotein inducers, P-glycoprotein substratesCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Nu-citalopram, Ng CitalopramPirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigationalPirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneum...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Pirfenidon Day Zero ehf. 267 mg Filmtabletten, Pirfenidon Day Zero ehf. 801 mg Filmtablettenalpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003Approved, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males … = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120].
Mixtures: One A Day Tab, One A Day Advance FemCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesNitric Oxide
go.drugbank.com/drugs/DB00435ApprovedInvestigationalNitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. … Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant.
Synonyms: NOCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalSodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour...
Mixtures: N-ORS Oral Rehydration Salts (Orange Flavour), U-Lite Effervescent GranulesProducts: Sodium Citrate Blood Pack Units, (PL 146 Plastic), Sodium Citrate Blood-Pack Units, (PL 146 Plastic)Glycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: Visine ALL DAY COMFORT DRY EYE Relief, No More ProductsCategories: Cytochrome P-450 CYP2E1 Inducers, Cytochrome P-450 Enzyme InducersMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide