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Displaying results 111 - 120 of 10000 in total
  1. Drug

    Dabigatran etexilate

    go.drugbank.com/drugs/DB06695
    ApprovedInvestigational

    Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran].

    Products: PRADAXA® 150 MG, Dabahib 150 mg-Hartkapseln
  2. Drug

    Procaine

    go.drugbank.com/drugs/DB00721
    ApprovedInvestigationalVet approved

    A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. … Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].

    Products: NTCAIN 100 MG/10 ML IM AMPUL, 10 ADET, NTCAIN 100 MG/10 ML IM AMPUL, 100 ADET
  3. Drug

    Darunavir

    go.drugbank.com/drugs/DB01264
    ApprovedInvestigational

    [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection.

    Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    [A39076] On the available products, ibuprofen is administered as a racemic mixture. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.

    Mixtures: COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML, Combogesic 500 mg/150 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth. … Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously.

    Synonyms: (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acidInternational brands: Caverject DC
  6. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer. … Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: DARITEX-A, CLORHIDRATO DE IRINOTECAN TRIHIDRATO 20 MG/ML
  7. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality

    Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  8. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].

    Mixtures: NIF TEN 50Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
  9. Drug

    Ceftibuten

    go.drugbank.com/drugs/DB01415
    ApprovedInvestigational

    Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered.

    Mixtures: WINCEF PLUS 180/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, BUCEF PLUS 180/62.5 MG TOZ ICEREN SASE, 20 ADETProducts: BUCEF 180 MG SASE, 20 ADET, WINCEF 180 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML
  10. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. … [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile.

    Mixtures: TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADET, APRANAX PLUS 550 MG/30 MG FILM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates