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Displaying results 1191 - 1200 of 10000 in total
  1. Drug

    Aprotinin

    go.drugbank.com/drugs/DB06692
    ApprovedInvestigationalWithdrawn

    The goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery. … For this use, it is typically administered by injection.

    Mixtures: ARTISS 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET, TISSEEL 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR 1 ADETProducts: Trasylol 10 000 KIE/ml Infusionslösung, TRASYLOL INJECTION 500,000 kiu/50 ml
  2. Drug

    Omalizumab

    go.drugbank.com/drugs/DB00043
    ApprovedInvestigational

    Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). … By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its receptors on immune cells.

    Products: XOLAIR ® 150 MG, XOLAIR 150 MG ENJEKSIYONLUK COZELTI İÇİN TOZ İÇEREN FLAKON, 1 ADET
  3. Drug

    Thiocolchicoside

    go.drugbank.com/drugs/DB11582
    Investigational

    It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663]

    Synonyms: Thiocolchicine 2-glucoside analogMixtures: LEODEX PLUS 50 MG/8 MG FILM KAPLI TABLET,10 TABLET, MUSCOFLEX DUO 50 MG/8 MG DEĞIŞTIRILMIŞ SALIMLI SERT KAPSÜL ,10 KAPSÜL
  4. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    FDA approved in 2009. … Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: SUGVİDA 10 MG FİLM KAPLI TABLET, 28 ADET, EFFIENT 10 MG FILM KAPLI TABLET, 28 ADET
  5. Drug

    Neomycin

    go.drugbank.com/drugs/DB00994
    ApprovedInvestigationalVet approved

    [L11979] It is also used in combination with [polymyxin B] sulfates and [hydrocortisone] in otic suspensions for use in the treatment of bacterial infections in the external auditory canal, including infections … [A191529] Neomycin sulfate as monotherapy is available in an oral solution for adjunct use in the treatment of hepatic coma.

    Mixtures: THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GR, THIOCILLINE 500 IU/G + 5 MG/G DERİ MERHEMİ, 30 GProducts: TP-NEOCIN 500 WSP NEOMYCIN SULPHATE 500MG/G POWDER, Neomycin 528.5 mg/g Water Soluble Powder
  6. Drug

    Midodrine

    go.drugbank.com/drugs/DB00211
    ApprovedInvestigational

    An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.

    Synonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol, (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  7. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.

    Synonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinCategories: MATE 2 Substrates, MATE 2 Substrates with a Narrow Therapeutic Index
  8. Drug

    Fludrocortisone

    go.drugbank.com/drugs/DB00687
    ApprovedInvestigational

    Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency. … [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ASTONIN-H 0,1 MG TABLET, 100 ADET, FLORINEF TABLET 0.1 mg
  9. Drug

    Diethylpropion

    go.drugbank.com/drugs/DB00937
    ApprovedIllicitInvestigational

    A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. … It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)

    Synonyms: 2-(diethylamino)propiophenone, 1-phenyl-2-diethylamino-1-propanoneProducts: NEOBES 50, Diethylpropion Hydrochloride ER
  10. Pathway

    Acylcarnitine 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine

    smpdb.ca/view/SMP0123498
    Metabolic

    11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoyl-CoA reacts with L-carnitine to form 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more