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Displaying results 1201 - 1210 of 10000 in total
  1. Drug

    Norleucine

    go.drugbank.com/drugs/DB15458
    Investigational

    Norleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women).

  2. Drug

    PD-0299685

    go.drugbank.com/drugs/DB15264
    Investigational

    PD-0299685 is under investigation in clinical trial NCT00314964 (Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause).

  3. Drug

    Dexchlorpheniramine maleate

    go.drugbank.com/drugs/DB09555
    Approved

    Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture. … Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine.

    Mixtures: Re Drylex, Corzall PE
  4. Drug

    GSK232802

    go.drugbank.com/drugs/DB16110
    Investigational

    GSK232802 is under investigation in clinical trial NCT00604825 (Treatment of Hot Flashes/flushes in Postmenopausal Women (WARM Study)).

  5. Drug

    Rineterkib

    go.drugbank.com/drugs/DB17560
    Investigational

    Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel

  6. Drug

    Hemoximer

    go.drugbank.com/drugs/DB17600
    Investigational

    Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.

  7. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Synonyms: (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridineMixtures: Pediatex TD, Stahist Tp
  8. Target

    High affinity immunoglobulin epsilon receptor subunit gamma

    go.drugbank.com/bio_entities/BE0000049
    TargetHumans

    As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. … As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset.

    Polypeptides: High affinity immunoglobulin epsilon receptor subunit gammaSynonyms: Fc receptor gamma-chain, IgE Fc receptor subunit gamma
  9. Target

    Gamma-aminobutyric acid receptor subunit rho-1

    go.drugbank.com/bio_entities/BE0000129
    TargetHumans

    Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (PubMed:37659407). Rho-containing GABA-gated chlorid...

    Polypeptides: Gamma-aminobutyric acid receptor subunit rho-1Synonyms: GABA(C) receptor, GABA(A) receptor subunit rho-1
  10. Target

    Mast/stem cell growth factor receptor Kit

    go.drugbank.com/bio_entities/BE0000453
    TargetHumans

    KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. … Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance

    Polypeptides: Mast/stem cell growth factor receptor Kit