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Allergic purpura
go.drugbank.com/conditions/DBCOND0102163Drugs: ChlorpheniramineSynonyms: Immunoglobulin A-associated vasculitis, Immunoglobulin A vasculitis (disorder)Sorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalSorafenib is a bi-aryl urea and an oral multikinase inhibitor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea, 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamideHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedMixtures: Alcortin A, Alcortin ACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, BSEP/ABCB11 Substrates with a Narrow Therapeutic IndexInternational brands: Digocard-GTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.
Mixtures: GANFORT 0.3MG/ML+5MG/ML ED, GANFORT 0.3MG/ML+5MG/ML EDCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesOctinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalOctinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. … It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun.
Mixtures: NARS FOUNDATION Santa Fe, NARS ALL DAY LUMINOUS FOUNDATION Santa FeCategories: Compounds used in a research, industrial, or household settingFrangula purshiana bark
go.drugbank.com/drugs/DB15478ApprovedMixtures: Le 100 B, C Ottways Lax TabProducts: Cascara Fluid ExtLoratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigationalLoratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: LARITOL EX, LARITOL EXCategories: P-glycoprotein inhibitors, P-glycoprotein substratesTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalTrabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically. … Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: TRABECTEDINA EG, Yolisar 1 mg I.V. İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 1 ADETApolipoproteins
go.drugbank.com/bio_entities/BE0010065CarrierTargetHumansLp(a) may be a ligand for megalin/Gp 330 … Appears to be able to transport a variety of ligands in a number of different contexts
Polypeptides: Apolipoprotein A-I, Apolipoprotein A-IISynonyms: Lp(a), Apo(a)