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Displaying results 1211 - 1220 of 10000 in total
  1. Pathway

    Ranitidine Action Pathway

    smpdb.ca/view/SMP0000230
    Drug action

    Ranitidine is an anti-ulcer agent, that works through antagonizing the histamine H2 receptor. It is used to reduce abdominal pain, heartburn, acid indigestion and acid reflux. The pathway begins in the stomach, where ranitidine inhibits ...

    Drugs: ATP · Ranitidine · Potassium cation · Zinc · Acetylcholine
    Enzymes: Potassium voltage-gated channel subfamily E member 2
  2. Pathway

    Famotidine Action Pathway

    smpdb.ca/view/SMP0000231
    Drug action

    Famotidine (also known as Pepcid) can bind and inhibit histamine H2 receptor on parietal cell's basolateral membrane. Binding of famotidine can effectively inhibit the histamine effects, which lead to reduced nocturnal gastric acid and b...

    Drugs: ATP · Famotidine · Potassium cation · Zinc · Acetylcholine
    Enzymes: Potassium voltage-gated channel subfamily E member 2
  3. Pathway

    Cimetidine Action Pathway

    smpdb.ca/view/SMP0000232
    Drug action

    Cimetidine, sold as Tagamet, is a compound related to histamine. It is a H2 antagonist drug, also called H2RAs or H2 blockers, and was the first of this class to be discovered. H2 antagonist drugs compete with histamine to bind to the hi...

    Drugs: ATP · Cimetidine · Potassium cation · Zinc · Acetylcholine
    Enzymes: Potassium voltage-gated channel subfamily E member 2
  4. Pathway

    Gastric Acid Production

    smpdb.ca/view/SMP0000589
    Physiological

    Gastric acid plays a key role in the digestion of proteins by activating digestive enzymes to break down long chains of amino acids. In addition, it aids in the absorption of certain vitamins and minerals and also acts as one of the body...

    Drugs: ATP · Potassium cation · Zinc · Acetylcholine
    Enzymes: Potassium voltage-gated channel subfamily E member 2
  5. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:0/14:1(9Z))

    smpdb.ca/view/SMP0015057
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  6. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:0/22:1(13Z))

    smpdb.ca/view/SMP0015077
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  7. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/14:0)

    smpdb.ca/view/SMP0015085
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  8. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/20:0)

    smpdb.ca/view/SMP0015097
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  9. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/22:0)

    smpdb.ca/view/SMP0015105
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  10. Pathway

    Phosphatidylethanolamine Biosynthesis PE(15:0/14:1(9Z))

    smpdb.ca/view/SMP0015115
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more