Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
- Mechanism
- Curator reviewed
Pharmacologically active on Muscarinic acetylcholine receptor M3
- Primary indication
- Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.Curator reviewed · 1 structured indication
- Formula / weight
- C7H16NO2 · 146.2074 g/mol (avg)
- First approval
- Canada, 2011 · United States, 1993
- Also known as
- Choline acetate · O-Acetylcholine
- Brand names
Resolves to
OIPILFWXSMYKGL-UHFFFAOYSA-NSMILESCC(=O)OCC[N+](C)(C)CWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Acetylcholine, and which of those have an active Phase 3 trial?
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