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Displaying results 1211 - 1220 of 10000 in total
  1. Drug

    Vestronidase alfa

    go.drugbank.com/drugs/DB12366
    ApprovedInvestigational

    Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. … Vestronidase alfa was FDA-approved on November 17th, 2017 under the trade name Mepsevii as an intravenous infusion for the treatment of pediatric and adult patients.

  2. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    A study was done on the clearance rate of vinorelbine on individuals with various single polymorphonuclear mutations. … Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998].

  3. Drug

    Caffeine

    go.drugbank.com/drugs/DB00201
    ApprovedInvestigational

    [L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. … Premature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung development and may eventually cause asthma or early onset emphysema in those born prematurely.

    Mixtures: Anacin ES, Re-action E
  4. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. … Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare.

    Synonyms: Vitamin E acetate, Vitamin E (alpha tocopherol acetate)Mixtures: Supravite Stress Avec Vit E Et Fer, Supravite Stress Avec Vit E Cuivre Et Zinc
  5. Drug

    Benralizumab

    go.drugbank.com/drugs/DB12023
    ApprovedInvestigational

    [A31293] Benralizumab was FDA approved on November 14, 2017, and was developed by MedImmune, AstraZeneca's global biologic research and development arm.[L1019] … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils

    Products: Fasenra Pen, Fasenra 30mg Solution for Injection in Pre-filled Pen
  6. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    It next appeared on the world scene for high volume (12-15cc), routine use, in diagnosing disc herniations. A number of clinicians have published on the dangers of oil myelography. … In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the

    Categories: Compounds used in a research, industrial, or household setting, Non-Watersoluble X-Ray Contrast Media
  7. Drug

    Atracurium besylate

    go.drugbank.com/drugs/DB00732
    Approved

    Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents … A non-depolarizing neuromuscular blocking agent with short duration of action.

  8. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.

    Mixtures: Arthritis Extra Strength Roll-ON LotionCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Non COX-2 selective NSAIDS
  9. Drug

    Propoxycaine

    go.drugbank.com/drugs/DB09342
    Approved

    Used in combination with procaine, it was the only dental local anesthetic available in cartridge form [L1592]. … Although no longer available in the United States, this medication was used in combination with procaine to aid in anesthesia during dental procedures [L1592].

  10. Drug

    Paritaprevir

    go.drugbank.com/drugs/DB09297
    ApprovedInvestigational

    In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Paritaprevir as a first line … In Canada, paritaprevir is also available as a fixed-dose combination product with [DB09296], [DB09183], and [DB00503] as the Health Canada-approved, commercially available product Holkira Pak.

    Synonyms: (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo