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Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigationalAgalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.
Products: REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, FABRAZYME 35 MG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ, 1 ADETPotassium bicarbonate
go.drugbank.com/drugs/DB11098ApprovedInvestigationalPotassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. … [L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.[L1837]
Mixtures: GASVİN MAX 1000 MG/200 MG ORAL SÜSPANSİYON, 200 ML, GALVİKS ADVANCE 1000 MG+200 MG/10 ML ORAL SÜSPANSİYON, 200 MLProducts: Effer-K 20 mEq Unflavored, Effer-K 20 mEq Orange CreamTrifluoperazine
go.drugbank.com/drugs/DB00831ApprovedA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Mixtures: Stelabid No 2, Stelabid No 1Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesDesoximetasone
go.drugbank.com/drugs/DB00547ApprovedA topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Synonyms: 9alpha-fluoro-16alpha-methyl-delta(1)-corticosterone, (11β,16α)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dioneMixtures: R-DIM®, Desoximetasone 0.05% / Niacinamide 4%Moxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnMoxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension.
Synonyms: (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acidCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsTerfenadine
go.drugbank.com/drugs/DB00342ApprovedWithdrawnIn the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-olPhenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnIt also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedionePyrvinium
go.drugbank.com/drugs/DB06816ApprovedInvestigationalWithdrawnPyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under inves...
Categories: Heterocyclic Compounds, 2-RingProducts: PIROK 50 ML SUSPANSIYON, PIROK SÜSPANSIYON, 25 MLMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalgeneric and as a brand name product. … Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair.
Mixtures: EVEREST-DX, BROCRIPTIN® 10 MG/ 5 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersCangrelor
go.drugbank.com/drugs/DB06441ApprovedInvestigationalCangrelor was approved by the FDA in June 2015 for intravenous application. … Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors.
Synonyms: [dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acidCategories: Heterocyclic Compounds, 2-Ring