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Displaying results 1231 - 1240 of 10000 in total
  1. Indication

    Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure

    go.drugbank.com/conditions/DBCOND0120023
    Drugs: Diazepam
    Synonyms: Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure
  2. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]

    Synonyms: AX, (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMixtures: AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S, AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S
  3. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    As with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.

    Mixtures: Arthritis Extra Strength Roll-ON LotionCategories: Non COX-2 selective NSAIDS
  4. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm.

    Synonyms: 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ester, isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylateCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household settingProducts: ENJ. ICIN COZ. ICEREN FLAKON, 10 ML, ENJ. ICIN COZ. ICEREN FLAKON, 15 ML
  6. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. … Cholestyramine resin is quite hydrophilic, but insoluble in water.

    Categories: Compounds used in a research, industrial, or household settingProducts: ANTILIP GRANULADO EN SACHET, COLESTYRAMIN 1A PHARMA 4G
  7. Target

    Pimeloyl-[acyl-carrier protein] methyl ester esterase

    go.drugbank.com/bio_entities/BE0001630
    TargetEnzymeEscherichia coli (strain K12)

    E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. … Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic acid into pimeloyl-CoA, a precursor in biotin biosynthesis.

    Polypeptides: Pimeloyl-[acyl-carrier protein] methyl ester esterase
  8. Drug

    Candesartan cilexetil

    go.drugbank.com/drugs/DB00796
    ApprovedInvestigational

    It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease. … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.

    Mixtures: CANDESARPLUS AL 32MG/25MG, CANDESARPLUS AL 8MG/12.5MGCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker
  9. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.

    Synonyms: N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)International brands: Prevacare R
  10. Drug

    Voriconazole

    go.drugbank.com/drugs/DB00582
    ApprovedInvestigational

    Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660]

    Synonyms: (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors