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Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe. … the use of baricitinib for the treatment of COVID-19 in May 2022.
Categories: Experimental Unapproved Treatments for COVID-19Padeliporfin
go.drugbank.com/drugs/DB15575ApprovedInvestigationalPadeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies. … [A244559] Vascular-targeted photodynamic therapy (VTP), or vascular targeted photochemotherapy, is a focal treatment for localized prostate cancer.
Categories: Heterocyclic Compounds with 4 or More RingsAnthralin
go.drugbank.com/drugs/DB11157ApprovedThe chemical structure of anthralin allows for dual solubility, permitting the compound to be absorbed well through the epidermis [A27276]. … It is a main active ingredient in topical skin formulations for the treatment of psoriasis. Various formulations of the drug are available, including solutions, foams, and shampoos [L1979].
Mixtures: PSORAKS 30 GR FORT KREMCategories: Antipsoriatics for Topical UseCapivasertib
go.drugbank.com/drugs/DB12218ApprovedInvestigational[A262021,A262026,A262031] On November 17th, 2023, capivasertib, under the brand name TRUQAP, was approved by the FDA for the treatment of adult patients HR-positive, HER2-negative locally advanced or … Therefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor.
Nirmatrelvir
go.drugbank.com/drugs/DB16691ApprovedInvestigational[L33354] 3CL<sup>PRO</sup> is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. … [L46921] Paxlovid was approved for use in Canada in January 2022 for the treatment of adult patients with mild-moderate COVID-19 [L39544] and later granted conditional marketing authorization by the European
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseCholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnNormally, it is an endogenous hormone but is available commercially for diagnostic processes and replacement in pancreatic insufficiency [L1646, L1647, L1648]. in the octapeptide form. … Cholecystokinin ( also known as _CCK or CCK-PZ_) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein.
Categories: Tests for Pancreatic FunctionPovidone K30
go.drugbank.com/drugs/DB14478ApprovedA polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See [povidone] for full details.
Cefapirin
go.drugbank.com/drugs/DB01139ApprovedVet approvedProduction for use in humans has been discontinued in the United States. Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseBovine type I collagen
go.drugbank.com/drugs/DB10771ApprovedInvestigationalBovine type I collagen is also used as a health supplement for bones and joints [A32698]. … Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing [L2427], [L2450].
Paramethasone
go.drugbank.com/drugs/DB01384ExperimentalIt has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, Plain